By precisely controlling the temperature and gas concentration, a high saturation humidity in the inner cavity is maintained. A high-temperature dry heat sterilization program at 140℃ or 180℃ is adopted to ensure cleanliness. At the same time, it is equipped with an ultra-long-life infrared (IR) carbon dioxide sensor that can withstand 190℃ to precisely control the carbon dioxide concentration and provide a stable cell culture environment. In addition, the comprehensively upgraded hypoxia control module can better simulate the in vivo environment, enhance cell growth performance, improve biological relevance, and protect the healthy growth of cells.